Against Nature, also known as Against the Grain, is a novel by Joris-Karl Huysmans, published in 1884. It follows the life of Jean des Esseintes, an eccentric aristocrat who retreats from society to indulge in his own aesthetic and decadent pleasures. The book explores themes of decadence, artifice, and the rejection of traditional values. Huysmans' vivid descriptions and detailed exploration of des Esseintes' extravagant lifestyle make this novel a quintessential example of fin-de-siècle literature.