The House-Museum of Lope de Vega is a historic house located in the Barrio de las Letras. It was the former residence of the renowned Spanish playwright and poet, Lope de Vega. The museum offers a fascinating insight into the life and works of Lope de Vega, showcasing his personal belongings, manuscripts, and other artifacts. It is a must-visit for literature enthusiasts and those interested in Spanish cultural history.