Against Nature, also known as Against the Grain, is a novel by Joris-Karl Huysmans, published in 1884. It follows the life of Jean des Esseintes, an eccentric aristocrat who retreats from society to indulge in his decadent and aesthetic pursuits. The novel explores themes of artifice, individualism, and the rejection of traditional values. It is a seminal work of Decadent literature.