In the horror-comedy film 'Little Monsters,' Lupita Nyong'o plays the role of Miss Caroline, a kindergarten teacher who must protect her students from a zombie outbreak during a field trip. Directed by Abe Forsythe, the film combines humor and horror to create a unique and entertaining experience. Nyong'o's performance as the brave and resourceful teacher adds a layer of heart and depth to the film. 'Little Monsters' showcases Nyong'o's versatility as an actress, as she effortlessly transitions between intense and comedic moments.