The Descent from the Cross is a masterpiece by Rogier van der Weyden, exhibited in the Prado Museum. It is a deeply moving and emotionally charged painting that depicts the moment when the body of Jesus Christ is taken down from the cross after his crucifixion. Van der Weyden's meticulous attention to detail, skillful use of light and shadow, and expressive figures create a sense of sorrow and grief. The painting is considered one of the most important examples of Northern Renaissance art and is admired for its technical brilliance and emotional impact.