Preacher is a comic book series created by writer Garth Ennis and artist Steve Dillon. It follows the story of Jesse Custer, a small-town preacher who becomes possessed by a supernatural entity known as Genesis, giving him the power to command anyone to do his bidding. Jesse embarks on a journey to find God and hold him accountable for abandoning his creation. The comic has been adapted into a TV series on Amazon Prime, which has garnered praise for its dark humor, complex characters, and thought-provoking exploration of faith and morality.