À rebours, translated as Against the Grain or Against Nature, is a novel by Joris-Karl Huysmans that is often regarded as a manifesto of Decadent literature. It follows the life of Jean des Esseintes, an aristocrat who withdraws from society to pursue a life of aesthetic indulgence and sensory excess. The book delves into themes of decadence, artifice, and the rejection of conventional morality, making it a significant work of the fin-de-siècle period.