Located in the trendy SoHo neighborhood, The Mercer Hotel offers smoke-free rooms with a sleek and modern design. The rooms feature floor-to-ceiling windows, luxurious bedding, and high-end amenities. Guests can enjoy the hotel's fitness center, courtyard garden, and on-site restaurant serving seasonal cuisine. The Mercer Hotel is also surrounded by fashionable boutiques, art galleries, and trendy restaurants. With its contemporary style and smoke-free environment, The Mercer Hotel is an excellent choice for those looking for a smoke-free hotel in Manhattan.