Georgia O'Keeffe was an American artist known for her large-scale paintings of flowers, New York skyscrapers, and landscapes of the American Southwest. She played a pivotal role in the development of American modernism and is often considered one of the most important female artists of the 20th century. O'Keeffe's unique style combined abstraction and representation, creating bold and vibrant compositions. Her notable works include Jimson Weed/White Flower No. 1, Black Iris, and Cow's Skull: Red, White, and Blue. O'Keeffe's art continues to captivate audiences with its sensual and evocative imagery.